Large-Scale Study Highlights Frequency of Drug-Gene Interactions

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Translational Software Inc, Bellevue, Wash, has completed a large-scale analysis of the medication lists of 505,000 patients to identify potentially harmful drug-gene interactions. Results of the analysis showed that 20% of patients had a pharmacogenetic profile associated with a severe drug-gene interaction with drugs on their current medication list. An additional 48% of patients had a profile that caused a moderate drug-gene interaction.1

According to the US Centers for Disease Control and Prevention, adverse drug events cause more than one million emergency department visits and 280,000 hospitalizations each year. CDC estimates that $3.5 billion is spent annually on excess medical costs to treat adverse drug events.

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